Keanu Baccus starts after making his return to the club from Mansfield earlier this week.
The Australian midfielder penned a two-year deal with the Saints and he's in from the start as manager Stephen Robinson makes two changes from the side that lost 1-0 away to Celtic last weekend.
Miguel Freckleton is the other change as he comes in for his debut at the back. Richard King and Fraser Taylor drop to the bench.
St Mirren: George, Fraser, Gogic, Freckleton, Richardson, Phillips, Baccus, O'Hara (c), John, Idowu, Mandron
Subs: Mullen, King, Sobowale, Tanser, Taylor, McMenamin, Calvin, Ayunga, Mooney
Motherwell: Ward, Koutroumbis, McGinn (c), O'Donnell, Longelo, Watt, Slattery, Fadinger, Maswanhise, Just, Said
Subs: Oxborough, Balmer, Sparrow, Stamatelopoulos, Halliday, Wilson, Ross, Forrest, Gillies
